Doctoral Defense: Philip Adamek
top-down wet milling approach in a molten carrier, the drug was selectively ground to the submicron (0.1‑1 µm) region. Using a custom‑built annular gap batch mill, SCS containing >90 % submicron particles were [...] surfactant sodium dodecyl sulfate as an additive, the redispersion of primary particles was achieved. At 1 wt.% the surfactant initiated a foaming process of the molten carrier, leading to the adsorption of …
